author(s)
Jagadish Naik M 1*, Samba Naik 2, Palaindira. P 3

abstract
The continuous use of pesticides over a period of time cannot sustain the crop yield and also harmful effects on soil and environment. Mulberry leaves are the predominant food source for silkworm, Bombyx mori rearing. The incidence of Pink mealy bug occurring in mulberry plantation can cause tukra disease that leads to qualitative loss of mulberry plantation. The present study was undertaken to study the effect of neem seed kernel extract having potential against the pests and insects as natural botanicals origin by foliar spray. The seed kernel extract of Azadirachta indica sprayed to occurring mealy bugs at the early cause of infection to V1 mulberry variety and reared to Silkworm. The total ammonia, urea and uric acid parameters were studied in tissue like haemolymph. The ammonia and uric acid activity gradually increased this increase however was significant at (P>0.05). There were a gradual decrease of urea level from day 3 to day 6, this decrease was however non-significant. Foliar spray of seed kernel extract hold greater promise for control of tukra infested mulberry leaves and did not affect the excretory system in silkworms.