Contact: +91-9711224068
Journal of Entomology and Zoology Studies
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal

ISSN Print: 2349-6800 | ISSN Online: 2320-7078

Journal of Entomology and Zoology Studies

updates
NAAS Rating: 5.53 NEW
2015, Vol. 3, Issue 2
Increased frequency of nuclear anomalies in exfoliated buccal mucosa of cigarette smokers

Abhay Singh Yadav, Manisha Saini

Smoking causes genetic damage associated with increased risk of oral cancer. Cigarette smoking induces genetic aberrations and micronucleus assay is a great biomarker to study the effect of smoking in human population. The present study was undertaken to detect incidence of nuclear anomalies in the exfoliated buccal epithelial cells of smokers using micronucleus assay. 100 healthy individuals (48 smokers and 52 non-smokers) were chosen randomly for the present study. A significantly high frequency of micronuclei was observed in the smokers (p<0.01) as compared to non-smokers. There was significant difference (p<0.05) in the frequency of binucleate cells and karyolysis depicting increased damage in the smokers. A dose-response relationship was observed between smoking and DNA damage.
Pages : 07-10 | 753 Views | 8 Downloads
How to cite this article:
Abhay Singh Yadav, Manisha Saini . Increased frequency of nuclear anomalies in exfoliated buccal mucosa of cigarette smokers. 2015; 3(2): 07-10.
Call for book chapter
Journals List Click Here Research Journals Research Journals
Please use another browser.