author(s)
Hidayat Khan, Jafar Khan, Usman Ali Khan, Anwar Sheed Khan, Muhammad Sohail, Malik Jan, Noor Zada Khan, Muhammad Ayub Jadoon, Azam Hayat, Ikram Ullah, Mujaddad Ur Rahman, Kiran Ismail and Khifsa Khan

abstract
Medicinal plants have been used for centuries, and various cultures still depend on the plants for their primary health care needs. In the present study selected plant Oxalis corniculata is collected from Bajaur region, Pakistan. The plants extracts were obtained and further fractionated into ethyl acetate, chloroform, n-hexane along with their aqueous extracts. By well diffusion method these plant extracts were screened against four skin selected bacterial pathogenic strains e.g. Staph. aureus, Streptococcus pyogenes, Staphylococcus epidermidis, Pseudomonas aeruginosa. Minimum inhibitory concentrations (MICs) were also determined of the selected plant extracts against selected bacteria. Results of MICs and well diffusion showed that Oxalis corniculata was more potent plant for activity against the selected skin pathogens. Phytochemical analysis showed that Oxalis corniculata consists of alkaloid, phenol, tannins and flavonoid in highest concentration. Phytochemical analysis also showed that hexane, ethyl acetate and chloroform were more effective in antibacterial potential while aqueous was less effective. Owing to this importance further research on these plants can be promising as agent for development of novel antibiotics.