The present In-vitro study was conducted at pathology laboratory, University of agricultural sciences, GKVK, Bangalore, Karnataka, India during February 2016 to evaluate animal products against rice blast disease caused by Pyricularia oryzae (Cav.). The five different animal products viz., cow milk, cow urine, butter milk, cow ghee and cow dung were tested at three different concentrations of 10, 20 and 30% by using the poisoned food technique. Among the five different animal products, highest percent inhibition of mycelial growth of fungus was recorded in cow ghee (96.33, 96.50 and 98.90%) at all the concentration tested with mean of 97.24 percent followed by butter milk with the inhibition of 86.07, 87.93 and 88.73 percent respectively with mean of 87.57 percent. Minimum inhibition was observed in cow dung, with 45.37, 53.67 and 67.17 percent inhibition at 10, 20 and 30 percent concentration respectively with a mean of 55.40 percent. In general, the inhibition of radial growth of fungus increased with increase in concentration of each animal product.