A study was conducted to investigate the tick infestation on cattle in the coastal district of Odisha from February 2016 to January 2017. During the period of study, 1176 out of 2920 cattle population revealed the presence of ixodid tick infestation. The most prominently infested ixodid tick belonged to Rhipicephalus (Boophilus) microplus (24.07%), followed by Hyalomma anatolicum (5.6%) and Rhipicephalus sanguineus (1.7%). The study showed that significant (p<0.05) high proportion of ticks were recorded in young cattle (< 1 year), indigenous cattle and cattle with poor body condition. The females showed higher infestation than males. The udder (35.03%) and inner thighs (27.55%) were the most common tick predilection site. Month wise prevalence study indicated that animals were infested throughout the year with maximum peak during May to August and lowest during November to January.