author(s)
N Peetambari Devi, SK Das, RK Sanjukta and SG Singh

abstract
The present investigation was conducted to assess the antibacterial activity of integumentary extract of freshwater fish species viz., Singhi (Heteropneustes fossilis) and Mrigal (Cirrhinus mrigala) and neem (Azadirachta indica) extracts (leaves and bark) against the selected microbes namely Aeromonas hyprophila and Staphylococcus aureus. Disc diffusion method was employed to determine the antibacterial activity of different extracts. In this study Heteropneutes fossilis integumentary secretions extract demonstrated greater inhibitory ability than Cirrhinus mrigala. It was also observed that Heteropneutes fossilis integumentary extract have more inhibitory effect against Aeromonas hyprophila (22±2.05) than Staphylococcus aureus (18±1.56). While, the ethanol extract of neem leaves was observed to possess higher antibacterial activity than that of neem bark extract. Interestingly, the neem leaves extract had shown more inhibitory activity against the Staphylococcus aureus (13±1.76) as compared to Aeromonas hyprophila (12±1.88). The study highlights the importance of fish integumentary and neem extracts as potential antibacterial agents.