author(s)
K. Lakshmi Devi, K. Yellamma

abstract
The present study has been aimed at examining severe perturbations in the Cholinergic system in different tissues like Silk Gland, Hemolymph, Fat body and Muscle of silkworm larvae treated with Zinc, vitamin, Pyridoxine and hormone, Methoprene. The experimental worms were divided in to four groups and fed with mulberry leaves soaked in the selected compounds i.e. Zinc chloride, Pyridoxine, Methoprene and with Mixed dose (Zn+B6+H). The Control group of silkworm larvae was fed with normal mulberry leaves. All groups of silkworm larvae were fed four times in a day throughout the 5th instar larval period. Both Control and Experimental silkworm larvae were weighedrndaily and sacrificed on selected days viz. 1st, 3rd, 5th and 7th day. Cumulatively, the findings of the present study suggest that the mixed dose significantly elevated the levels of ACh and declined the AChE activity in all selected experimental groups except Control.