Wolbachia is an intracellular alpha-proteobacteria Rickettisial endosymbiont present in most of the arthropods. Wolbachia a parasite in insects invades its host biology in many ways, including cytoplasmic incompatibility, feminization, male killing, parthenogenesis and reproductive fitness advantage. The whole genome sequence of Wolbachia reveals the function of several genes like wsp (Wolbachia surface protein) FtsZ (Wolbachia cell division protein) and ANK (ankarin domain protein). Among these, FtsZ (Filamenting temperature sensitive) protein plays a vital role in the cell division of Wolbachia .In the present study, we characterized the Wolbachia FtsZ gene infected uzifly, Exorista sorbillans a serious menace to silkworm Bombyx mori L. The study revealed the possible implications of FtsZ gene to combat the uzifly E. sorbillans an endoparasite of B. mori L.