The present in vitro study was conducted during 2013-2014 to observe Malathion induced toxicity on oviduct of goat (Capra hircus) with an aim to provide help in understanding the cases of early abortion, fertility complications and sterility. Malathion exposure was given at two concentrations- 1nM and 100nM; both exposed for 4 hours and 6 hours; alongwith zero hour control for each treatment. Maximum damage in oviduct tissue was observed after 6 hours of exposure to 100 nM Malathion. In isthmus the mucosal folds were disrupted after pesticide exposure. Width of mucosal folds was also found to be reduced alongwith erosion of apices portion of mucosal cells. Higher damage to ciliated and secretory cells was noticed in 100 nM treatment as compared to 1nM. Appearance of gaps alongwith separation of submucosa and mucosa was also prominent after 6 hours of 100 nM Malathion treatment. Structure of mucosal and sub mucosal lining was also remarkably distorted following pesticide treatment. Serosa layer also revealed high damage following Malathion exposure.