author(s)
A Topchiyeva and FZ Mammadova

abstract
Activity of hyaluronidase in venom of a honey bee Apis mellifera L. caucasica from various regions of Azerbaijan was studied. The highest mean activity of hyaluronidase was in the venom collected in Zaqatala (103.1 IU/mg), the lowest activity was in the venom, collected in the surrounding the city of Baku (69, 5 IU/mg). The activity of hyaluronidase in venom was determined depending on the seasons of the year. The highest enzyme activity in the venom collected in all regions was established in summer and lowest in autumn. The results of the experimental data can be used for determining the biological activity and quality of bee venom for the manufacture of drugs based on apitoxin.