author(s)
Priya R, Uma T, Saravanan N and Jothi Narendiran N

abstract
An investigation was carried out to study the efficacy of synthetic detergent on hepatocyte changes in Tilapia mossambica. In these experiments study we used detergent expose to 60 numbers of fish individuals for five month durations. The Study was divided into two (Control and Experiment) groups containing 30 individuals in each group. The control group, the fishes were exposed to proven pure water from our laboratory; Department of Zoology, the experimental group fishes were exposed to 1ppm dilution of commercial biodegradable detergents. The control and experiment study group was replicated to confirm the results. The hepatocyte observed in the control group shows the homogeneous cytoplasm and central nucleus. The experiment fish hepatocytes shows with the nuclei displaced to the periphery, some of the vacuolized nuclei or at the beginning of vacuolization process. The present results suggest the detergents were affected the fish morphology and physiological process. Future, we investigate the biochemical and metabolically aspect of these fishes of T. mossambica.