author(s)
Alam Zeb, Ikram Ullah, Hameed Ur Rehman,Mujaddad Ur Rehman, Muhammad Ayub Jadoon, Inam Ullah, Israr alam, Rizwan Ullah, Zaffar Iqbal and Muhammad Fazal Hameed and Azam hayat

abstract
Pseudomonas aeruginosa is a leading cause of nosocomial infections. Antibiotic susceptibility patterns of Pseudomonas aeruginosa varied markedly with the antibiotic tested. In this study a total of 40 clinical specimens were investigated, 10 were from females and 30 for males. Most of them belonged to the age group 10-60 years. Urine and blood were the more noticeable sources of specimens of Pseudomonas aeruginosa. Most isolates of Pseudomonas aeruginosa showed maximum resistance to Azithromycin (90%) and Oxacillin (75%), they showed less resistance to Cefoperazone+ Sulbactam (10%) and Imipenam (25%). All isolates were sensitive to the Amikacin, Ofloxacin and Tobramycin. Present study shows the occurrence of resistance and sensitivity to various anti-pseudomonal agents. Cefoperazone + Sulbactam were the only anti-pseudomonal drug against the Pseudomonas aeruginosa was fully sensitive. We recommend a more limited and a more rational use of this drug in this hospital setup. Amikacin and Imipenam are the choice drugs for optimal management of infections caused by Pseudomonas aeruginosa.