Wound healing and anti-bacterial efficacy of Rheum emodi and its different extracts on excisional wounds in rabbits
Nida Handoo, Jalal-ud-Din Parrah, Hakim Athar, Mohmmad Abrar Gayas, Taziyun Imtiyaz and Syed Bisma
Encouraging results from the past studies regarding the use of R. emodi as a wound healing agent, necessitates the full exploration of this herb for its efficacy in wound healing. The present study was aimed to evaluate the wound healing and anti-bacterial efficacy of R.emodi and its ethanolic, aqueous and petroleum ether extracts in excisional wounds in thirty healthy rabbits randomly assigned in five equal groups. Three excisional wounds (1.5×1.5 cm) on the dorsal spine were created in all under general anesthesia. Except for the first group treated with povidone iodine which served as control, all the other groups were treated with R.emodi and its extracts. Animals in the treated groups showed prompt and better healing in the following order: Petroleum ether extract > Aqueous extract > Ethanolic extract > Crude dust powder > Control group.
Nida Handoo, Jalal-ud-Din Parrah, Hakim Athar, Mohmmad Abrar Gayas, Taziyun Imtiyaz, Syed Bisma. Wound healing and anti-bacterial efficacy of Rheum emodi and its different extracts on excisional wounds in rabbits . J Entomol Zool Stud 2018;6(1):1204-1213.