Soybean (Kharif 2015-16) germplasms were studied for antibiosis and antixenotic effects against Spilarctia obliqua (Walker). In antibiosis study, JS 2089, JS 2087, VLS 89, MACS 1460, DSB 25 and Bragg showed resistance exhibiting lower larval weight, pupal weight, higher pupal period, larval period and terminal larval mortality as compared to other. In antixenosis SL 688, VLS 89, PS 1556, RCS 1046, JS 2089 and PS 1347 exhibited lower ECI, ECD value; VLS 89, SL 688, RCS 1046, NRC 94, PS 1550 and JS 2087 showed higher AD value and less preferred by the test insect. In SL 955, PS 1550, JS 2087, MACS 1460, NRC 94 showed higher ECI, ECD values. In SL 955, MACS 1460, PS 1347, JS 2089, PS 1556 showed lower AD values indicating that these germplasm preferred by the insects. DSB 25 and JS 335 having C value ranged from 1.03 and 1.00 for Spilarctia obliqua.