Comparative efficacy of a combination of albendazole and praziquantel; ivermectin and fenbendazole against gastrointestinal nematodiasis in dogs
CD Thangjam, PN Mahanta, G Mahato, DK Deka, S Sarma, SS Begum and S Islam
Gastrointestinal parasitism is one of the common causes of diseases of dogs. Factors associated with the prevalence and risk for mechanical transmission of a number of canine gastrointestinal nematodes, and the role of dogs in such transmission has been a worldwide concern. The present study was undertaken as a part of P.G research work to evaluate the comparative efficacy of three commercially available anthelmintics viz. Ivermectin (Neomec), Fenbendazole (Panacur) and a combination of Albendazole and Praziquantel (Praziplus). A total of 24 dogs of different age, sex and breeds positive for gastrointestinal helminthic infection were randomly divided into 4 groups for the study. An experimental 30 days of observation period revealed that administration of a single dose of Ivermectin (@ 200 g/kg body weight) resulted into early reduction of EPG, than oral administration of Fenbendazole (@ 50 mg/kg body weight for three consecutive days) or an oral administrationof a single dose of a combination of Albendazole and Praziquantel (@ 1 tab/kg body weight). Further, the overall percent efficacy of Ivermectin, Fenbendazole and a combination of Albendazole and Praziquantel was found to be 96.47%, 93.25% and 92.49% respectively. Also, Fenbendazole was found to be effective and safe anthelmintic for therapeutic use in pups and adults against gastrointestinal nematodiasis.
CD Thangjam, PN Mahanta, G Mahato, DK Deka, S Sarma, SS Begum, S Islam. Comparative efficacy of a combination of albendazole and praziquantel; ivermectin and fenbendazole against gastrointestinal nematodiasis in dogs. J Entomol Zool Stud 2018;6(2):1292-1295.