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Journal of Entomology and Zoology Studies
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ISSN Print: 2349-6800 | ISSN Online: 2320-7078

Journal of Entomology and Zoology Studies

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2018, Vol. 6, Issue 2
Insilico analysis of Listeriolysin-O with its natural inhibitors

Sudam Chandra Sahoo, Sarada Prasanna Sahoo, Rashmi Ranjan Mishra, Madhu R and Satsarthak Tripathy

Present study was conducted to understand the molecular interaction of listeriolysin-O with its natural inhibitors such as Fisetin and Lutein. The crystal structure of protein listeriolysin-O was revealed and molecular docking study was conducted by AutoDock tool. The result was analysed in terms of binding energy and position of binding. Further the interacting of amino acid residues was analysed. The energy obtained from docking study of Lutein was -6.05 whereas for fisetin was -4.75. It was identified that, both inhibitors possessed the strong interaction with listeriolysin-O. Hence lutein and fisetin may represent promising therapeutic agent for treatment of Listeriosis.
Pages : 1987-1990 | 321 Views | 17 Downloads
How to cite this article:
Sudam Chandra Sahoo, Sarada Prasanna Sahoo, Rashmi Ranjan Mishra, Madhu R, Satsarthak Tripathy. Insilico analysis of Listeriolysin-O with its natural inhibitors. J Entomol Zool Stud 2018;6(2):1987-1990.
Journal of Entomology and Zoology Studies
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