author(s)
Sushmita Sastya, Mukund Chouhan, Vikas Karunakaran and Nirmala Jamra

abstract
CRISPR/Cas9 is the newly discovered revolutionary genome editing tool by which to manipulate the DNA of variety of organism and that allows the scientist to studies on functional genome of parasites. It play important role in improvement of science of Parasitology. Structural and functional genomics information helps in investigation of the relationship between parasite and their host. CRISPR/Cas9 based gene editing studies have been shown and found to be successful on several parasites including Leishmania donovani, Toxoplasma gondii, Trypanosome cruzi, Strongyloides stercoralis, Cryptosporidium species and Mosquitoes. Data from these studies could provide the experimental basis for applications related to early diagnosis, treatment and disease prevention.