Fish farming is the world’s fastest-growing sector of agricultural business. Consumer demand for fish products is increasing. At the same time, wild fish stocks are rapidly declining, mainly because of over-fishing. Increased public demands for fish and dwindling natural marine habitats have encouraged scientists to study ways that biotechnology can increase the production of fish and shellfish. The science of biotechnology has endowed us with new tools and tremendous power to create novel genes and genotypes of plants, animals and fish. The application of biotechnology in the fisheries sector is a relatively recent practice. Nevertheless, it is a promising area to enhance fish production. The increased application of biotechnological tools can certainly revolutionise our fish farming besides its role in biodiversity conservation.