Effect of dietary exposure to diazinon on different organs and hematological parameters of rabbit
MA Hassan, T Rahaman, KA Ferdous, MNH Parvez and MS Islam
The irrational use of diazinon in our country can play a crucial role in the occurrence of many diseases of animals and human. The present study was conducted to investigate the alteration of gross & microscopic study of various organs, hematological parameters of rabbit as effect of insecticide (Diazinon). A total number of 16 male rabbits were assigned into four group. Control group received only basal diet and the other groups T1, T2 and T3 received diazinon with supplemented feed at a dose level of 15, 30 and 45mg/kg feed respectively. Remarkable decreased in weight gain in T3 group. Diazinon caused elevation of SGPT/ALT (P<0.01), serum creatinine level attributed to pathological lesions. Histopathological lesions in liver included cirrhosis and necrosis in only (T2 & T3) treated groups. In kidney, glomerulus was filled with reactive cells in group T1. There was slight loss of normal histological structure of pancreas in group T1 rather than group T2 & T3.