author(s)
Brahmanand, Omprakash Shrivastava, Satyanidhi Shukla, Akshay Kumar and Rajesh Kumar

abstract
The present study was conducted to describe the effects of intrauterine infusion of methanol fraction of neem oil and extract of neem bark in the treatment of sub-clinical endometritis in repeat breeder cattle. A total of 100 repeat breeder cattle were screened from college livestock farm, organized dairy farm and farmer^,s door in and around Jabalpur. After recording history, all the animals were subjected to gynaeco-clinical examination and White side test. A total of thirty repeat breeder cattle with sub-clinical endometritis were selected and randomly divided into five groups. The group I cattle i.e. control group were administered with 25 ml normal saline at 24 hrs. Interval for three days. Group II and III were administered with methanol fraction of neem oil for the different time interval. Group IV and V were administered with neem bark extract. Efficacy of both preparations was assessed by Fern pattern, pH of CVM, white side test and conception rate. The results indicate that administration of neem oil at 24 hrs. Interval for two days retrieved the cattle from sub-clinical endometritis. All cattle (100% in group II) showed negative to white side test. Further, the conception rate (83.33%) was obtained in neem oil fraction treated cattle at 24 hrs. interval than other treatment groups. On the basis of the present investigation, it is concluded that infusion of neem oil fraction at 24 hrs. interval for two days was found as the most effective treatment among all treated groups and, thus, can replace conventional antibiotic in the future for sub-clinical endometritis leading to repeat breeding condition in cattle.