author(s)
Dr. Keneisevono Kipu, Dr. Keneisezo Kuotsu, Dr. Neithono Kuotsu, Dr. KC Nath and Dr. MK Tamuli

abstract
A study was conducted on 8 sows to record the response of the uterus following intrauterine administration of lipopolysaccharide, a known immunomodulator by collecting uterine lavage from live animals, the immune response of the uterus was measured in terms of total leukocyte count (TLC) and differential leukocyte count (DLC), the mean TLC of uterine lavage collected from live animals was 1.57±0.21 × 10⁶/ml before intrauterine infusion of LPS and 1.17±0.29 × 10⁶/ml after infusion. In control group the mean values were 2.46±0.58 and 1.12±0.50 × 10⁶/ml respectively. Mean percentage of neutrophils in the uterine lavage collected from live sows before and after intrauterine infusion of LPS was 99.88±0.10 and 99.82±0.05 respectively. For lymphocyte the corresponding mean percentages were 0.13±0.10 and 0.19±0.05. In the control live sows treated with PBS the mean percentage of neutrophils in the uterine lavage was 99.88±0.10 and 99.75±0.07 before and after infusion respectively, and that of lymphocyte was 0.13±0.10 and 0.25±0.07 respectively, the study revealed that intrauterine infusion of E coli lipopolysaccharide did not affect the total leukocyte count and differential leukocyte count of the uterus in pigs.