The protective effects of Withania somnifera on biochemical profile of hepato-renal and endocrine system in fenvalerate exposed cockerels
PV Tikore, PR Rathod, RS Ingole, MV Khodke and KK Khose
After acclimatization for a period of one week, a day old 80 cockerels were randomly divided into four equal groups comprising 20 birds in each. Group T1 (control); group T2 was treated with fenvalerate @ 300 mg/kg of feed; group T3 was treated with Withania somnifera @ 200 mg/kg of feed and group T4 was given fenvalerate @ 300 mg/kg of feed with Withania somnifera @ 200 mg/kg of feed for four weeks and withdrawal of treatment for seven days. At 5th week as well as at 6th week serum AST and ALT showed significant (P≤0.05) increase in fenvalerate treated (T2) group while T4 group showed improvement. At the end of 5th week T2 group showed significant (P≤0.05) increase in BUN, creatinine, GGT and cholesterol but significant (P≤0.05) decrease in serum total protein, albumin, globulin, triiodothyronine, thyroxine and triiodothyronine: thyroxine ratio when compared with control and T4 group. From the present results it is concluded that Withania somnifera has protective effects on the various biochemical parameters against fenvalerate toxicity.
PV Tikore, PR Rathod, RS Ingole, MV Khodke, KK Khose. The protective effects of Withania somnifera on biochemical profile of hepato-renal and endocrine system in fenvalerate exposed cockerels. J Entomol Zool Stud 2019;7(5):1174-1177.