author(s)
Dr. Divya Patel, Dr. GP Lakhani, Dr. A Jain, Dr. RPS Baghel, Dr. KPS Saini and Dr. Nirbhay Kumar

abstract
The present research work was designed to study the Effect of Probiotic and Prebiotic on Cell-Mediated Immune Response and Economics of Rearing of Murrah Buffalo Calves. Total 18 Murrah buffalo calves with similar body weight of either sex at the age of 15^th day were selected and divided into 3 groups randomly and each group contains 6 animals. Group T1 (Control) was fed basal ration, group T2 was fed basal ration with Probiotic (Saccharomyces cerevisiae) @4g/animal/day and group T3 was fed basal ration with Prebiotic (Mannan oligosaccharide) @4g/animal/day. The duration of experiment was 3 months. The expenditure (#/kg) incurred for milk was 11952, 12096 and 12048 in T1, T2 and T3 groups respectively. The expenditure (#/kg) incurred for calf starter were 299, 276 and 310 in T1, T2 and T3 groups respectively. The expenditure for Probiotic and Prebiotic (#) were 52 and 40 in group T2 and T3 groups respectively. Total expenditure (#/calf) on milk, feed, fodder and feed additives were 12751, 13003 and 12938 in group T1, T2 and T3 groups respectively.