author(s)
Mahendra Mohan Yadav

abstract
A clinical investigation was conducted to determine the antibiotic sensitivity pattern of Klebsiella pneumoniae isolated from diarrheic goats. From 54 diarrheic goats, Klebsiella pneumoniae were isolated from 13 samples. Antibiotic sensitivity pattern for antibiotics revealed that highest resistance was observed in Ampicillin, Amoxycillin / Clavulanic acid, Penicillin and Tetracycline (100.0% each), followed by Co-trimoxazole (92.31% each), Cefachlor, Ceftriaxone, Cefotaxime, and Cefoperazone (61.54% each). The least antimicrobial resistance was observed in Gentamicin and Ciprofloxacin (15.38% each), followed by Chloramphenicol (7.69%). All the isolates are sensitive to Enrofloxacin and Levofloxacin. Multiple antimicrobial resistances ranging from 5 to 11 antimicrobials were observed in all the 13 isolates. Seven major antimicrobial resistance patterns were observed involving 6 to 13 isolates. Eleven isolates were showing resistance to minimum 5 antimicrobials. Multidrug resistant strains of Klebsiella pneumoniae in goats diarrheal cases are a matter of great concern as resistance genes are easily transferable to other species of Enterobacteriaceae family with potential to cause a disease and warrants a nearly possible transmission in human population. The paucity of reliable and timely information, particularly in Indian conditions, may further limit epidemiological surveillance of Klebsiella pneumoniae and effective stewardship efforts.