author(s)
Nishchal Dutta, Jasmine Banga, Sidhartha Deshmukh and Harmanjit Singh Banga

abstract
This pathological study deals with 7 day old pup which suffered from canine herpes virus (CHV) infection. Macroscopically, typical multifocal patches of haemorrhages with white necrotic centre in lungs along with various other organs were observed. The knowledge of its transmission was not known till the presence of typical intra nuclear inclusion bodies in all major organs including endothelial cells of blood vessels was noted microscopically. The pathologic changes in eye, cerebral parenchyma, endothelial cell lining of blood vessels and myocardial cells, besides major splanchanic organs clearly demonstrated possible haematogenous transmission of viral particle following in transplacental infection. Interestingly, vivid pathologic description of ocular and cerebral changes, in addition to the myocardial and endothelial cells involvement has been attempted to deliver the first ever information following naturally occurring infection of canine herpes virus in neonatal pup in India.