author(s)
Neha Gupta, VS Rajora, Kapil Kumar Gupta and Niddhi Arora

abstract
In the present investigation therapeutic efficacy of polyherbal formulation were evaluated in diarrhoeic calves of upto 6 weeks of age of either sex at Instructional Dairy Farm (IDF) of the university. Polyherbal formulation (PHF) was prepared by mixing equal proportions of extract of dried fruits of Aegle marmelos, roots of Zingiber officinale, leaves of Dalbergia sissoo, seeds of Eugenia jambolana and dried fruits of Emblica officinalis. PHF mixture was fed to the diarrhoeic calves @ 10 gm, BID for 5 days. The collected faecal samples were examined for E. coli and Salmonella by culture and biochemical method and Toxocara and Eimeria by flotation method using saturated salt solution. The therapeutic efficacy of polyherbal formulation was evaluated in diarrhoeic calves based on clinical examination, clinical profiles, haematological study, biochemical analysis and percent recovery. Twelve, diarrhoeic calves selected for therapeutic studies were divided in 2 equal groups of 6 calves each. Six healthy calves served as control and kept in group I. The animals of group II were treated with tab Tariflox OZ (500 mg Ornidazole and 200 mg Ofloxacin) @ 10 mg/kg body weight twice a day orally along with intravenous fluid (Ringer lactate) according to dehydration status of calves, whereas group III was treated with PHF along with intravenous fluid. Both the treatments were given for a maximum period of 5 days in both the groups or till recovery which is earlier. All animals of both the groups were recovered after therapy of their respective group however the duration of therapy required for complete recovery is more in case of group III. Further it has been observed that therapy with polyherbal formulation along with intravenous fluid administration is more economic (Rs. 129.37 per calf) as compared to therapy applied in group II (Rs. 180.06 per calf). Evaluation of clinical profile score indicates fluid therapy along with antibiotic is more superior than fluid therapy with polyherbal formulation. On the basis of these findings it can be concluded that poor farmers should go for polyherbal therapy along with fluid administration in case of calf diarrhea however for the financially strong farmers antibiotic administration is not the limiting factor so they can adopt alternate antibiotic therapy with consideration of side effect and antimicrobial resistance.