author(s)
Shaik Maimonaparveen, D Madhuri, M Lakshman, B Anilkumar, M Lakshmi Namratha, Y Ravikumar and K Sandhyarani

abstract
The ameliorative potential of whole Pomegranate fruit juice was studied against Bleomycin (BLM) induced toxicity on body weights (b.wts) and hematological parameters in rats. A total of 48 male albino Wistar rats were procured and divided into 4 groups consisting of 12 rats in each. The group 1 - control, group 2 - BLM {@ 5 mg/kg b.wt via single intra-tracheal (IT) instillation}, group 3 - BLM (@ 5 mg/kg b.wt via single IT instillation) + Pomegranate juice (@ 1 mL/rat once daily orally) and group 4 - Pomegranate juice (@ 1 mL/rat once daily orally). The experiment was carried out for a period of 28 days and six rats from each group were sacrificed on 14^th and 28^th day of the experiment. Significantly (P<0.05) reduction in b.wts were recorded in group 2 rats. All the hematological parameters were significantly reduced except total leukocyte count in BLM treated rats.