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Journal of Entomology and Zoology Studies
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P-ISSN: 2349-6800, E-ISSN: 2320-7078

Journal of Entomology and Zoology Studies

2022, Vol. 10, Issue 6
The effects of mangrove plant leaves (Acanthus ilicifolius) collected in can Gio district on white mice (Mus musculus var. albino) with diabetes

Long Le, Ngoc-Anh Nguyen, Ly-Thai-Uyen Thi and Thi-Tan-Luong Nguyen

This study was conducted to evaluate the hypoglycemic potential of mangrove plant leaves (Acanthus ilicifolius) fluid in white mice with diabetes mellitus with doses of mangrove leaves fluid of 100 mg/kg, 200 mg/kg, 300 mg/kg, 400 mg/kg corresponding to EX1, EX2, EX3, EX4, CT2. Diabetic mice had study results after 7 days. In EX1, EX2 and EX3 there was a decrease in blood glucose levels, after 7 days the results were 225.39 mg/dl respectively; 219.16 mg/dl and 201.55 mg/dl both had values greater than 200 mg/dl indicating that rats in these trials still had diabetes. In EX4, hypoglycemia with a dosage of 400 mg/kg mangrove leaves extract showed good therapeutic ability when blood glucose levels decreased to 178.36 mg/dl (<200 mg/dl). When studying, histological analysis of diabetic white mouse kidney on H&E staining specimens, kidney tissue cells, glomeruli had structural and functional changes. The above results show that mangrove plant leaves extract has the ability to lower blood glucose levels and protect kidney tissue and glomeruli from damage, limiting the level of kidney cancer caused by diabetes.
Pages : 54-59 | 410 Views | 170 Downloads


Journal of Entomology and Zoology Studies Journal of Entomology and Zoology Studies
How to cite this article:
Long Le, Ngoc-Anh Nguyen, Ly-Thai-Uyen Thi, Thi-Tan-Luong Nguyen. The effects of mangrove plant leaves (Acanthus ilicifolius) collected in can Gio district on white mice (Mus musculus var. albino) with diabetes. J Entomol Zool Stud 2022;10(6):54-59. DOI: 10.22271/j.ento.2022.v10.i6a.9127

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