In Traditional System of Medicine (TSM) several edible plants are used for the management of inflammation. Inflammation is one of the immune response processes of the body which shows four types of indications: redness, pain, burning and swelling. Plant possess the ability for synthesizing a number of phytochemicals to defend themselves that are known as secondary metabolites that can be uses for the treatment of inflammation in the body. Medicines used for anti-inflammatory activity are steroidal and non-steroidal in allopathic system of medicines (ASM) which are available in the market frequently used by the patients However; it causes several side effects including blood clotting and increasing risk of heart-attacks. Hence, herbal medicines are safe as compared to allopathic medicines and considered as herbal products. Therefore, there is a need to conduct clinical trials based on the findings of pioneer workers who have compiled the data for the treatment of inflammation using phytochemicals of plant origin by applying advanced techniques and scientific approaches.