Arthropod pests, particularly insects, pose a significant threat to global agricultural production, leading to substantial economic losses and jeopardizing food security. The extensive use of synthetic insecticides for pest control has resulted in several detrimental effects, including the development of resistant insect populations and ecological damage. This review explores the potential of entomopathogenic microorganisms as a sustainable and environmentally friendly alternative for pest management. It highlights the safety, specificity, and positive impact on biodiversity associated with microbial control. Additionally, the review discusses the increasing utilization of microbial pesticides and emphasizes the need for streamlined registration procedures to promote their widespread commercialization. Overall, this review aims to underscore the manifold benefits of employing microbial control to mitigate the adverse effects of pest insects on agriculture and the environment.