Spirocerca lupi, a spirurid nematode responsible for causing tumorous growth in splanchanic organs of canine is eventually incriminated for neoplastic transformation. The present case noted in an eleven month old mongrel dog with oesophageal nodular growth having neoplastic transformation following S. lupi infection was histologically elaborated with possible pathologic mechanism. An additional occult clinical entity i.e. spontaneous cellutis, widely seen across the two sides of thoracic ribs was discussed. This report further entails special description of parasite involved and pathology noted in spontaneous cellutis due to unknown reason (aetiology) and illustrated distantly located pyogranulomatous lesions in kidney.